LRU – RESEARCH UNIT INSTITUTE OF PEDIATRICS OF SOUTHERN SWITZERLAND

MEMBERS:

PD Dr.ssa med. Barbara Goeggel Simonetti

PD Dr.ssa med. Federica Vanoni

PD Dr. Med Mattia Rizzi

Dr.ssa med. Amalia Stefani-Gluecksberg

SECRETARIAT/COORDINATOR:

Sig.ra Alessia Severi Conti

The pediatric research unit promotes and coordinates the mainly clinical research in different fields of pediatrics. Examples of current research projects are given below.

• Cardiology-Nephrology: childhood hypertension, cardiovascular risk factors in the young, Kawasaki disease.
• General Pediatrics: Systematic reviews of rare diseases, or rare complications of frequent pediatric diseases.
• Infectious disease: We are involved in several registries (MoCHIV, CITRUS) that analyze the prevalence of rare infectious diseases in childhood.
• Neuropediatrics: neurovascular, neuroinflammatory, diseases, epilepsy, autism spectrum disorder (Auto-Play D in collaboration with SUPSI), outcome after premature birth, perinatal asphyxia or in children with congenital heart disease, and cerebral palsy.
• Onco-hematology: we are involved in 31 international studies (oncology protocols)/registry. We contribute to a non-interventional study for treatment of patient with hemophilia A with and without inhibitors (EMIL, Roche).
• Rheumatology: we participate to an international cohort rheumatology diseases registry. We strictly collaborate with the CHUV for the development of observational prospective and retrospective studies on treatment and outcome in inflammatory diseases.
• Pediatric Surgery: minimal invasive surgery, orthopedic and surgical trauma.

• IPSI conducts mainly clinical research. Locally we closely collaborate with the CTU EOC, USI, and SUPSI. Through our researchers and as a member of SwissPedNet, we are connected with the other pediatric research units and participate in multicenter clinical trials at a national and international level. The pediatric CTU provides assistance to researchers throughout every step of a research project, with a particular commitment to promote young colleagues. We aim at performing high quality research in accordance with the Human Research Act, national and international guidelines. Thanks to this connection we have the opportunity to participate in multicentric (randomized) trial.
• Our internationals allows us to be involved in international multi-centre studies
• From a local perspective, we conduct retrospective, observational, interventional studies and systematic reviews, promoting young researchers.
• Adhere to local SOPs order to ensure high quality in clinical research