11a Giornata della Ricerca e dell’Innovazione in Medicina Umana della Svizzera italiana

Below the FINAL PROGRAM of the

11a GIORNATA DELLA RICERCA E DELL’INNOVAZIONE IN MEDICINA UMANA DELLA SVIZZERA ITALIANA
which took place on FRIDAY 3 JUNE 2022 in hybrid mode

E-POSTER SESSION
VIRTUAL SESSION

 

BASIC TRANSLATIONAL OR COMPUTATIONAL RESEARCH

Claudia Altomare – A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes

Carolina Balbi – Cardiomyocytes (CM) derived small Extracellular Vesicles (sEV) plays an important role in heart development

Linda Bernasconi – Characterization of air bubbles generated by perfusionist maneuvers during cardiopulmonary bypass

Jonathan Besomi – Automatic classification of diseases using deep learning approaches

Adalgisa Condoluci – Evaluation of the different stratification models for POD24 prediction in patients with follicular lymphoma

Vincenzo De Rosa – In-hospital development and implementation of 3D personalised custom-made cut guides for pediatric limb malalignement

Nicolò Formaggio – Identifying New Targets Involved in Androgen Receptor Expression Loss in Advanced Prostate Cancer

Jacopo Galafassi – The role of gut microbiome in anastomotic leakage after colorectal cancer surgery (MicrobAL)

Francesca Guidetti – Targeting IRAK4 in marginal zone lymphoma models with secondary resistance to PI3K and BTK inhibitors

Anaïs Lamouline – Biofabrication of a bone marrow model for breast cancer bone metastasis personalized medicine

Claudia Magrin – A Tau-dependent mechanism of epigenetic modulation of gene expression

Laura Marciano – The use of mobile assessments for monitoring mental health in youth: An umbrella review

Federico Menor Fusaro – 3D planned ACL reconstruction in pediatric knees. The Ticino experience

Hassan Mohsin – The absence of intestinal microbiota impairs the activity of the Cre-lox system in a mouse model of conditional Paneth cell depletion

Ester Piovesana – Patient-Derived Fibroblasts and Induced Neurons (iNS) for the Study of Cellular Pathways Involved in Neurodegeneration and Lysosomal Storage Disorders

Matin Salehi – Fragmentome profiling reveals distinct molecular subgroups of Classic Hodgkin lymphoma

Elena Vacchi – Altered immune activity of plasmatic extracellular vesicles derived from Parkinsons Disease patients

CLINICAL OR EPIDEMIOLOGICAL RESEARCH 

Jacopo Albanese – Joint arthroplasty after intra-articular steroid injections: the risk of post-operative infections

Michele Bedulli – CPR/DNR conversations with patients in the internal medicine ward: Physician-reported practices in Ticino

Matteo Beretta-Piccoli – Muscle Fiber Conduction Velocity Correlates With the Age at Onset in Mild FSHD Cases

Marco Bongiovanni – Twenty kilometers is a World away: impact of COVID-19 on multi-resistant, hospital-acquired, bacterial infections in Italy

Luca Bonomo – Grade 1 and 2 Chest Wall Chondrosarcomas: CT Imaging Features and Review of the Literature

Davide Brucato – Complications of Non-Permanent Facial Fillers: A Literature Review

Maria Caiata Zufferey – Home Treatment for acute mental disorders: challenges and opportunities for patients, families, and healthcare providers

Christian Candrian – Volar Locking Plate VS Cast Immobilization for Distal Radius Fractures: A Systematic Review and Meta-analysis

Serena Caverzasio – Impairment of sleep homeostasis in cervical dystonia patients

Giacomo Chiaro – Skin Biopsy has a high Diagnostic Yield in Sistemic Amyloidosis and Polyneuropathy

Giulio Conte – Atrioventricular block of unknown etiology in young adults with pacemaker implantation: an epidemiological and genetic study

Laura De Pellegrin – Effects of NPWTi-d versus NPWT or Standard of Care in Orthoplastic Surgery: A Systematic Review and Meta-Analysis

Dea Degabriel – Patient experience of communication with the medical team of the emergency department

Marco Delcogliano – Randomized controlled study of the ligamentization process and graft integration in the reconstruction of the anterior cruciate ligament with or without detachment of the tibial insertion of the semitendinosus and Gracilis tendons of the knee: intermediate analysis

Andrea Demarchi – Catheter ablation of atrial fibrillation in patients with partial anomalous pulmonary venous return: An international multicenter registry and a literature review

Pietro Feltri – Platelet-Rich Plasma Does not Improve Clinical Results in Patients with Rotator Cuff Disorders but Reduces the Retear Rate. A Systematic Review and Meta-Analysis

Anna Folli – Evaluating the extent of pain in adolescents: preliminary results on test-retest reliability

Alessandra Franzetti-Pellanda – Perceptions, opinions and feelings of cancer patients during COVID 19 pandemic

Eleonora Garosi – Clinical evolution and therapeutic implications in patients with TIR1C nodules according to ICCRTC: a retrospective analysis

Pietro Giacopelli – Covid-free surgical pathways for acute cholecystectomy

Martina Iattoni – Effect of structured briefing prior to patient arrival on interprofessional communication and collaboration in the trauma team

Viviana Lo Cicero – Cartilage Microtissues (CARTIBEADSTM) for therapeutic applications: towards a FIM clinical trial

Qianfeng Lu – Preparing of advanced end-of-life care planning in Switzerland: the potentials of patient-centered healthcare

Francesca Mangili – Risk models for perinatal depression based on the life-on study

Francesco Martucci – Fast thermoradiation therapy: a new approach available at the Radiation Oncology Clinic, IOSI

Anna Messina – Weathering the storm in seeking support: a qualitative study with caregivers of people with dementia

Eleonora Maddalena Minerva – Rural-urban disparities in lung cancer surgical treatment pathway: the paradox of a rich, small region

Caterina Mollica – Augmented Reality navigation during percutaneous pedicle screw placement: clinical results from a prospective multicenter study

Francesco Mongelli – Reoperative bariatric surgery after primary laparoscopic gastric plication for morbid obesity: A systematic review and meta-analysis

Andrea Stefano Monteleone – Patients with Rotator Cuff Tendinopathy Present a Psychological Impairment, not only a Functional Deficit. A Systematic Review

Susanna Morlino – Applying the Health Belief Model to explain cybersecurity behaviors of hospital employees

Astrid Navarra – Reimbursement policies of Swiss insurance companies for reduction mammaplasty for treatment of symptomatic breast hypertrophy

Lorenzo Massimo Oldrini – Proximal Humerus Fractures: Delto-Pectoral ORIF vs Delto-Split MIPO. What is the Best Surgical Approach?

Deborah Pacifico – Subjective cognitive decline and its associations with psycho-affective symptoms and disability: a cross-sectional study

Georgios Popeskou Sotirios – Bowel recovery after intra vs extracorporeal anastomosis for oncologic laparoscopic right hemicolectomy within an ERAS protocol: a retrospective study

Giulia Pretelli – An integrated immune-metabolic score predicts outcome in advanced lung carcinoma patients treated with immunotherapy

Giorgio Raia – CT-Derived Body Composition and Complications After Pneumonectomy in Lung Cancer: Time for a Sex-Related Analysis?

Stefania Maria Rita Rizzo – O-RADS Stratification System in Pelvic MRI: a Meta-Analysis of Diagnostic Performance and Misclassification Rates

Alessandro Schneebeli – Intra-rater reliability of a shear wave tensiometer in the evaluation of Achielles tendon mechanical properties

Sebastiano Spampatti – Three-points mesh fixation in robot-assisted transabdominal preperitoneal (R-TAPP) repair of 208 inguinal hernias: Short and long-term results

Elena Trevisi – Genetic Counseling and Germline Testing for Men with Prostate Cancer: A Two-Year IOSI Experience

Fabio Turco – Preliminary results from SIESTA, a Pilot Observational Study Investigating Sleep Quality in Prostate Cancer Patients

NURSING RESEARCH

Alex Alamo Nottaris – L’Impatto Mentale Della Pandemia Covid-19 Sugli Infermieri Di Medicina Intensiva: Una Ricerca Qualitativa

Ilaria Bordin – Prospettiva infermieristica sull’ottimizzazione del time to therapy nell’ictus iperacuto presso l’Ospedale Regionale di Lugano

Lidia Braga – Sensibilizzazione interattiva nella camera degli errori rivolta al personale infermieristico con focus sul processo farmacologico

Alexa Calisto Maia – Ex-tubo” La disfagia postestubazione: il ruolo dell’infermiere di medicina intensiva nella sua valutazione e prevenzione

Daiana Campani – Validazione transfrontaliera di uno strumento per il reporting delle cadute a domicilio

Mara Catena – Triage Avanzato Medico Infermieristico al Pronto Soccorso Ospedale Civico Lugano

Omar Consonni – Leadership models compared with new generations of healthcare employees

Sena Pasic – Percorso formativo infermieristico: “Gestire con competenze esperte il paziente sottoposto a chirurgia toracica

Claudio Speroni – The perception of Shared Governance among the nursing staff

POSTER SESSION
EXHIBITION PRINTED POSTER (IN PRESENCE)

BASIC TRANSLATIONAL OR COMPUTATIONAL RESEARCH

6B. Antoine Buetti-Dinh – Mining the Cancer Genome Atlas (TCGA) database: the case of proteasome genes and exportin-1

9B. Maria Vittoria Colombo – Engineering the process of Endochondral Ossification to study Ewing Sarcoma

Paolo Conflitti – Coarse-graining of Funnel-Metadynamics calculations: an ultra-fast approach for estimation of ligand binding free energies

15B. Angela Elia – Tumour-associated early neutrophil progenitors specifically infiltrate Luminal-B breast cancer biopsies

16B. Giuseppe Vassalli (Maximilian Emmert) – Intracoronary delivery of cardiac-derived exosomes is beneficial in a translational model of acute myocardial infarction

19B. Riccardo Francescato – Mesofluidic platform for the skeletal muscle fibrosis modeling.

21B. Lia Gander – Fast Characterization of Inducible Regions of Atrial Fibrillation Models with Multi-Fidelity Gaussian Process Classification

30B. Sebastiano Marinelli – 5-ALA induced Protoporphyrin (PpIX) fluorescence quantification for glioblastoma surgical resection

36B. Siddhartha Mukherjee – Tumour-infiltrating immature myeloid cells impair homologous DNA repair in hormone-dependent breast cancers promoting sensitivity to PARP-inhibition

37B. Nicolo Pernigoni – Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis

39B. Simone Pezzuto – Learning cardiac activation maps from 12-lead ECG with multi-fidelity Bayesian optimization on manifolds

41B. Alessio Bruscaggin (Maria Pirosa) – Circulating tumor DNA improves interim PET accuracy in classic Hodgkin lymphoma

46B. Mikhail Rudinskiy – Quantitative steady-state and time-resolved analyses of protein and organelle delivery to endolysosomes using HaloTag-GFP Reporter

51B. Martina Sola – Tau as a Novel Modulator of the Oncosuppressor Protein P53

52B. Elisa Sorrenti – Interplay between gut microbiota, specific IgA and tumor-associated neutrophils in human colorectal cancer

55B. Arianna Vallerga – Decoding Post-Translational Modifications of Prostate Cancer Progression

56B. Pedro Ventura – Concomitant deletion of Shp-1 and Shp-2 in T cells fails to improve anticancer responses

 

CLINICAL OR EPIDEMIOLOGICAL RESEARCH

1C. Pamela Agazzi – Longitudinal kinetics and prognostic power of serum neurofilament light after cardiac arrest.

5C. Lorenzo Bernardi – Robotic versus laparoscopic liver resection: propensity matched comparison of two-center experience

6C. Enos Bernasconi (Katharina Kusejko) – Integrated phylogenetic analysis of Austrian and Swiss HIV-1 sequences reveal differences in transmission patterns of the local HIV-1 epidemics

13C. Chiara Camponovo – One single calcitonin testing in thyroid nodule to detect or exclude medullary carcinoma

17C. Samantha Epistolio (Marco Cefalì) – KRAS mutational status may predict immune checkpoint inhibitors efficacy in NSCLC showing PD-L1 overexpression (TPS≥50%)

21C. Ruggero Cresta – Out-of-hospital management and outcome of ST-elevation acute coronary syndromes in Swiss Canton Ticino: 10 years of the preH-ACS registry

22C. Alessandra Cristaudi (Lorenzo Bernardi) – Introducing minimally invasive liver surgery in a tertiary center of Southern Switzerland: reappraisal of the first 100 consecutive cases

23C. Marco Barbero (Cinzia Cruder) – Risk factors of playing-related disorders among European music students. Results of the Risk of Music Students (RISMUS) longitudinal multicentre study

37C. Elia Rigamonti (Pietro Gianella) – Clinical, radiological and functional outcomes in patients with SARS-CoV-2 pneumonia: a prospective observational study

45C. Tanja Fusi-Schmidhauser (Marco Marando) – 1-year radiological, functional and quality-of-life outcomes in patients with SARS-CoV-2 pneumonia – A prospective observational study

46C. Francesco Marbach – Sling vs Brace after Surgery for Supraspinatus Tears: A Randomized Controlled Trial.

47C. Francesco Marchi – Prevalence of Localized Amyloid in Ligamentum Flavum of Patients with Lumbar Spinal Stenosis

50C. Silvia Miano – Clinical and genetic characteristic of narcolepsy type I patients with HLA negative

60C. Flavia Piciacchia – General practitioner management of patients with inherited arrhyhtmia syndromes: a canton ticino statewide survey

64C. Silvia Pozza – The validity and tolerability of awake calibration of the TOF Watch SX® monitor: An interventional prospective multicenter study

68C. Greta Rizzi – COVID-19 effects on cognition: a case-control study in adults and older adults from Ticino.

74C. Davide Sparasci – Restless Legs Syndrome and Periodic Limb Movements during Sleep in Multiple Sclerosis

75C. Ledingham N. Susan, Bernardi Lorenzo (Alessandro Torre) – Opioid-free anesthesia in bariatric surgery: a propensity score-matched analysis

80C. Yael Van der Geest – Outcome of patients with lacunar strokes in the era of thrombectomy: an analysis of the swiss stroke registry

14h05
New Technologies: PARALLEL SESSION

Chair: Eng. Alessandro Puiatti and Prof. Marco Barbero

6 Oral presentations (Presentation 8 min + Discussion 4 min)

Chiara Arrigoni (Daniele D’Arrigo) – Development of a patient-matched microfluidic arthritic joint model as a tool for personalized therapies.

Simone Bersini (Valerio Mainardi) – A novel mesoscale human muscle-tendon-bone interface model for the study of musculoskeletal diseases.

Dalila Petta – Towards a bone-on-a-chip with physiological trabecular structure by combining biomimetic coating and high-resolution 3d printing.

Diego Ulisse Pizzagalli – A trajectomics approach to manage complications of advanced chronic liver disease.

Pietro Luca Ratti – Wrist actigraphy can detect REM sleep behavior disorder in Parkinson’s disease.

Gianna Riccitelli (Leonardo Sacco) – Effects of rTMS treatment on social cognition abilities in mild cognitive impairment: preliminary results.

14h05
Nursing Research: PARALLEL SESSION 1

14h05
Basic, translational or computational research: PARALLEL SESSION 1

15h50
Nursing Research: PARALLEL SESSION 2

15h50
Base, translational or computational research: PARALLEL SESSION 2

Below the composition of the SCIENTIFIC COMMITTEE of the

11a GIORNATA DELLA RICERCA E DELL’INNOVAZIONE IN MEDICINA UMANA DELLA SVIZZERA ITALIANA
which took place on FRIDAY 3 JUNE 2022 in hybrid mode

 

Chairs:

• Prof. Greta Guarda PhD, Vice Decana per la Ricerca, Facoltà di scienze biomediche USI, Lugano e Responsabile del Laboratorio di “Immune Mechanisms”, IRB, Bellinzona
• Prof. Dr. med. Giorgio Treglia, Responsabile Servizio Ricerca ed Innovazione, Area Formazione accademica, Ricerca e Innovazione, Direzione generale EOC, e Caposervizio di Medicina Nucleare, Istituto di Imaging della Svizzera Italiana, EOC, Bellinzona

Members:

• Prof. Dr. med. Emiliano Albanese, Direttore dell’Istituto di Public Health USI e Professore Ordinario Facoltà di scienze biomediche USI, Lugano
• Prof. Marco Barbero, PhD, Rehabilitation Research Laboratory 2rLab, DEASS-SUPSI, Manno
• Loris Bonetti, PhD, RN, Responsabile Ricerca infermieristica, EOC, Bellinzona e Docente DEASS-SUPSI, Manno
• Sandro Bonetti, MD, Internal medicine, Physician, Dongio
• Dr.ssa Arianna Calcinotto, PhD, Responsabile del Laboratorio di Immunoterapia del cancro, IOR, Bellinzona
• Prof. Dr. Alessandro Ceschi, MD, MSc, Chief Physician and Medical and scientific director Institute of Pharmacological Sciences of Southern Switzerland, EOC, Deputy Chief Academic Education, Research and Innovation Area General Directorate EOC, and Director Clinical Trial Unit EOC (CTU-EOC), Lugano
• Prof. Dr.ssa med. Giandomenica Iezzi, Responsabile del Laboratorio di ricerca traslazionale del Dipartimento di chirurgia EOC, Bellinzona
• Prof. Dr. Vittorio Limongelli, Pharm.D., PhD, Full Professor in Pharmacology, Faculty of Biomedical Sciences, Euler Institute, USI Lugano
• Sarah Jayne Liptrott, PhD, RN, Lead for Nursing Research – ORBV, EOC, Bellinzona, and Nurse Researcher – IOSI, EOC, Bellinzona
• Prof. Dr. med. Giacomo Simonetti, Primario e Direttore medico e scientifico dell’Istituto di Pediatria della Svizzera Italiana e Professore Ordinario Facoltà di scienze biomediche USI, Lugano
• PD Dr. med Anastasios Stathis, Responsabile medico della Ricerca clinica, Istituto Oncologico della Svizzera Italiana, EOC, Bellinzona
• Prof. Marco Valgimigli, (MD), PhD, deputy Chief of Cardiology, Cardiocentro Ticino Institute
• Dr. Luca Varani, PhD, Responsabile del Laboratorio di biologia strutturale IRB, Bellinzona
• Michele Villa, RN, Responsabile dell’ Unità di Ricerca Infermieristica, Istituto Cardiocentro Ticino, EOC, Lugano
• Prof. Chiara Zecca, Chief of Service, Neurocenter of Southern Switzerland, EOC and Faculty of biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.

Event location: USI Campus Est, Settore A, Via la Santa 1, Lugano-Viganello

BY TRAIN Recommended!
Reach the Train Station Lugano. From the station, the campus EST of the Università della Svizzera italiana can be reached by bus or on foot.

 

BY BUS Recommended!
Take bus 6 (direction “Cornaredo”), which leaves from the square in front of the station; get off at the “University Campus” stop (about an 8-10 minute ride under normal traffic conditions).

See also the directions on the Map

ON FOOT Recommended!
From the station square go to Via Zurigo until you reach Corso Elvezia on the left and continue on Via Madonetta until you reach the bridge, cross it and on the left you will see the EST campus of the Università della Svizzera italiana.

See also directions on the map.

BY CAR STRONGLY DISCOURAGED!
A2 freeway: take the Lugano Nord exit, Lugano North Motorway. Proceed in a southerly direction on Autostrada Lugano Nord
44 s (800 m), Take Via Besso in the direction of Via S. Gottardo 5 min (1.5 km). Continue on Via S. Gottardo 57 s (450 m). Continue on Via Zurigo. Drive in the direction of Via la Santa 5 min (1.8 km). Arrival at Campus EST USI Via la Santa 1, 6962 Lugano

Shortly after the traffic lights crossing the bridge, the entrance to the campus underground parking lot is visible on the left.

See directions on the Map.

IMPORTANT IF YOU CANNOT REACH THE EVENT WITHOUT A CAR

An alternative parking lot in the immediate vicinity of the campus is the Lugano Italian Hospital parking garage (accessible from Via agli Orti): See directions on the Map.
At the city of Lugano link below you can find other parking in the area: https://www.lugano.ch/mobilita-sicurezza/parcheggi-e-autosili.html

 

 

Below is the LIST OF CREDIT REQUESTED for the

11a GIORNATA DELLA RICERCA E DELL’INNOVAZIONE IN MEDICINA UMANA DELLA SVIZZERA ITALIANA
which took place on FRIDAY 3 JUNE 2022 in hybrid mode

• SIWF FMH ISFM: 8 credits as part of extended continuing education
• Divisione della salute pubblica – Ufficio del veterinario cantonale – Sperimentazione animale: 0.5 day continuing education
• GSASA – Swiss Association for Public Health Administration and Hospital Pharmacists: 50 points FPH in hospital pharmacy and 50 points FPH in clinical pharmacy
• SWaPP Swiss Association of Pharmaceutical Professionals: 7.5 credit points

We found the following object, do you know to whom does it belong?

Please contact laura.dipetto@eoc.ch

In the coming weeks you will receive your personal certificate of attendance from the e-mail address: clinicaltrialunit@eoc.ch.
If you do not receive your certificate and for further questions, please contact us via the same e-mail.

Below the PRESS AND MEDIA of the

11a GIORNATA DELLA RICERCA E DELL’INNOVAZIONE IN MEDICINA UMANA DELLA SVIZZERA ITALIANA
which took place on FRIDAY 3 JUNE 2022 in hybrid mode

11a Giornata della Ricerca e dell’Innovazione in Medicina Umana della Svizzera italiana e presentazione del Rapporto scientifico EOC 2021.
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Giornata della ricerca e dell’innovazione, Il Quotidiano.
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“Una realtà piccola” che favorisce la ricerca.
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Sempre più reti e collaborazioni internazionali: così cresce la ricerca biomedica in Ticino.
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Ricerca e innovazione tra USI e SUPSI.
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Special thanks to:

Prof. Paolo Paganetti
Prof. Andrea Alimonti
Dr. stat. Alessandra Spitale
Inf. MSC Yvonne Willems Cavalli
Inf. MSc Annette Biegger
Prof. Giovanni Pedrazzini
Prof. Alain Kaelin
Prof. Mario Bianchetti
Prof. Michele Ghielmini
Prof. Mariagrazia Uguccioni (assente)
Dr. Fabrizio Barazzoni (assente)

BEST ORAL PRESENTATION

Tommaso Virgilio for the abstract entitled:
IL-1α secreted by macrophages promotes melanoma metastases in the sentinel lymph node by upregulating STAT3 signaling in the tumor

BEST POSTER

Riccardo Francescato for the abstract entitled:
Mesofluidic platform for the skeletal muscle fibrosis modeling

BEST ORAL PRESENTATION

Maria Pirosa for the abstract entitled:
A phase-II trial of clarithromycin and lenalidomide in relapsed/refractory MALT lymphomas: IELSG40

BEST POSTER

Francesco Marchi for the abstract entitled:
Prevalence of Localized Amyloid in Ligamentum Flavum of Patients with Lumbar Spinal Stenosis

BEST ORAL PRESENTATION

Sabine Caminada Van Den Bosch for the abstract entitled:
Follow-up clinico infermieristico presso il Centro di Senologia della Svizzera Italiana (CSSI)

BEST POSTER

Elena Corina Luca for the abstract entitled:
Nursing care in response to the care needs of patients with COVID-19: a mixed-methods study