This event has passed.

13a Giornata della ricerca e dell’Innovazione in Medicina Umana della Svizzera Italiana

27 September 2024 / 8:00 - 18:00

It is with great pleasure that the Clinical Trial Unit (CTU) EOC, Area Formazione medica e Ricerca (AFRi) EOC and Università della Svizzera italiana (USI), invite you to the

13^th Giornata della Ricerca e dell’Innovazione in Medicina Umana della Svizzera italiana to be held online and in presence on

FRIDAY 27 SEPTEMBER 2024

The deadline for submission of Abstracts in the three categories of RESEARCH below is now CLOSED:

- CLINICAL OR EPIDEMIOLOGICAL
- BASIC, TRANSLATIONAL OR COMPUTATIONAL
- NURSING

The programme of this 13th edition includes afther the opening, two Keynote Lectures, parallel sessions with oral presentations of the results of research projects carried out in Ticino, and the usual poster exhibition and discussion.

In addition, the following prizes will be awarded:

- Best oral presentation and poster clinical or epidemiological research
- Best oral presentation and poster basic, translational or computational research
- Best oral presentation and poster nursing research

The best oral presentations in the three categories will be voted by the participants onsite and online, and the event will end with an award ceremony and a final aperitif to close with a convivial moment.

The preliminary program is available by clicking on “PRELIMINARY PROGRAM” (see below) and is regularly updated.

Looking forward to meeting you in person in Lugano we wish you a nice summer!

The Organizing Team.

REGISTRATION 13a GIORNATA ONLINE

REGISTRATIONS are now open to participate ONLINE at the

13^th Giornata della Ricerca e dell’innovazione In Medicina Umana

ONLINE REGISTRATION DEADLINE

26 SEPTEMBER 2024
23:59 CET

AT THE LINK

2024/09/26 23:59:00

Are you an EOC user? Then register like this:

When you click on the registration link, the event window will open. Click on Register with Zoom Account blue button

Then log in via SSO (SSO access is represented by a key – see image below)
Enter in the appropriate box, if asked, the company domain: eoc-ch
Enter your e-mail and EOC password

NOTE: IF YOU REGISTER WITH THE EOC E-MAIL, YOU WILL HAVE TO USE THE SAME LOGIN AT THE EVENT DAY!

SCIENTIFIC COMMITTEE 13th GIORNATA

Below the Scientific Committee Members of the

13^th Giornata della Ricerca e dell’innovazione In Medicina Umana

Presidents:

Prof. Dr. Greta Guarda, Vice Decana per la Ricerca, Facoltà di scienze biomediche USI, Lugano e Responsabile del Laboratorio di “Immune Mechanisms”, IRB, Bellinzona
Prof. Dr. med. Giorgio Treglia, Responsabile Servizio Ricerca, Area Formazione medica e Ricerca, Direzione generale EOC, e Caposervizio di Medicina Nucleare, Istituto di Imaging della Svizzera Italiana, EOC, Bellinzona

Members:

Prof. Dr. med. Emiliano Albanese, Direttore dell’Istituto di Public Health USI e Professore Ordinario Facoltà di scienze biomediche USI, Lugano
Prof. Dr. Arianna Baggiolini, Responsabile del Laboratorio di Cellule Staminali e cancro, IOR, Bellinzona
Prof. Dr. Marco Barbero, Direttore del Laboratorio di ricerca in riabilitazione 2rLab, DEASS-SUPSI, Manno
Dr. Loris Bonetti, RN, Responsabile Ricerca infermieristica, EOC, Bellinzona e Docente DEASS-SUPSI, Manno
Dr. med. Sandro Bonetti, Medicina interna generale, medico di famiglia, Dongio
Prof. Dr. Arianna Calcinotto, Responsabile del Laboratorio di Immunoterapia del cancro, IOR, Bellinzona
Prof. Dr. med. Dimitri Christoforidis, Viceprimario Chirurgia e Chirurgia Viscerale, Dipartimento di Chirurgia EOC, Lugano
Prof. Dr. med. Pietro Cippà, Primario Nefrologia e Capo Dipartimento di Medicina EOC, Lugano
Prof. Dr. med. Alessandro Ceschi, MSc, Primario e Direttore medico e scientifico dell’Istituto di Scienze Farmacologiche della Svizzera Italiana EOC, Capo Area Formazione medica e Ricerca, Direzione generale EOC, e Direttore CTU-EOC, Lugano
Prof. Dr. med. Gianluca Di Tanna, Responsabile Servizio Ricerca, DEASS-SUPSI, Manno
Dr. med. Alessandra Franzetti Pellanda, Primario Radioterapia e Responsabile Unità di Ricerca Clinica, Clinica Luganese Moncucco, Lugano
Prof. Dr.ssa med. Giandomenica Iezzi, Responsabile del Laboratorio di ricerca traslazionale del Dipartimento di Chirurgia EOC, Bellinzona
Prof. Dr. Vittorio Limongelli, Responsabile del Laboratorio di Farmacologia computazionale, Istituto Eulero USI e Professore Ordinario Facoltà di scienze biomediche USI, Lugano
Dr. Sarah Jayne Liptrott, RN, Responsabile dell’Unità di Ricerca infermieristica ORBV-IOSI, EOC, Bellinzona
PD Dr. med. Mattia Rizzi, Caposervizio, Responsabile e Specialista Emato-Oncologia pediatrica, Istituto Pediatrico della Svizzera italiana, EOC, Bellinzona
Prof. Dr. med Anastasios Stathis, Responsabile medico della Ricerca clinica, Istituto Oncologico della Svizzera Italiana, EOC, Bellinzona
Prof. Dr. med. Marco Valgimigli, Vice-Primario del Servizio di Cardiologia, Istituto Cardiocentro Ticino EOC, Lugano
Dr. Luca Varani, Responsabile del Laboratorio di biologia strutturale IRB, Bellinzona
Michele Villa, RN, Responsabile dell’ Unità di Ricerca Infermieristica, Istituto Cardiocentro Ticino, EOC, Lugano
Prof. Dr. med. Chiara Zecca, Caposervizio Clinica di Neurologia, Istituto di Neuroscienze cliniche della Svizzera Italiana EOC, Lugano

PRELIMINARY PROGRAM

Here is the preliminary programme of the

13^th GIORNATA DELLA RICERCA E DELL’INNOVAZIONE IN MEDICINA UMANA DELLA SVIZZERA ITALIANA
which will be held on FRIDAY 27 SEPTEMBER 2024 hybrid mode

08h00
Welcome and Registration
08h30
Opening and special thanks

Greta Guarda, Chair Scientific committee 2024
Giorgio Treglia, Chair Scientific committee 2024

Glauco Martinetti, EOC General Director
Patrick Gagliardini, USI Pro Rector for Research

Special thanks and Communications from the Chief of Medical Education and Research Area, General Directorate EOC, Prof. Alessandro Ceschi

Presentation of:

Farma Industria Ticino, Piero Poli (Rivopharm SA), Chair
Swiss Medtech, Giuseppe Perale, Executive VP & Founder I.B.I. SA, Regenera SA, Chair Swiss Medtech Ticino
09h00
TOP RATED ORAL PRESENTATIONS: SESSION 1

(VOTING SESSION BY PARTICIPANTS IN PRESENCE AND ONLINE)

Chair: Giorgia Melli and Marco Valgimigli
7 Oral presentations (Presentation 7 min + Discussion 3 min)

Loris Bonetti – Psychometric characteristics of the NUrsing Behavioural Engagement (NUBE) Scale: a two-phases validation study
Marco Fabbro – Monitoring the activity of Halo-tagged ER-phagy receptors
Antonio Landi – Abbreviated or Standard Antiplatelet Therapy After PCI In HBR Patients with Chronic Kidney Disease
Andrea Milzi – Validation of different acute kidney injury scores in patients undergoing transcatheter aortic valve replacement
Stefano Panella – Extracellular Vesicles as Biomarkers for Monitoring Cellular Rejection after Heart Transplant
Greta Rizzi – Unveiling the metaphors of care: understanding dementia through language
Elena Vacchi – Tau seeding activity in skin biopsy is a novel diagnostic tool for brain neurodegenerative diseases
10h10
COFFEE BREAK
10h30
KEYNOTE LECTURE
Discussant: Alessandro Ceschi
Title: Advanced X-ray imaging for improved diagnostic
Prof. Dr. Marco Stampanoni
Center For Photon Science at Paul Scherrer Institut and Institute for Biomedical Engineering at ETH Zürich
11h00
PARALLEL SESSION: ONCOLOGY 1

Chairs: Arianna Calcinotto and Alessandra Franzetti-Pellanda
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Clemence Aellen – Efficacy of intraoperative widening of surgical resection margins of non-palpable breast cancer
Gaston Fabian Dellaferrera – Recurrence after resection for non-small cell lung cancer: risk factors by stage molecular profile
Chiara Fasana – The immune landscape of epithelial ovarian cancer
Maria Luisa Gasparri – Radar localization for targeted axillary dissection in breast cancer patients undergoing primary systemic treatment
Cindy Garda – Myeloid cells impact HER2 expression in breast cancer, affecting response to HER2-targeted therapy
Concetta Guerra – An antibody-based strategy targeting oncogenic mERG in prostate cancer
Giuseppe Salfi – Prognostic Implications of Early Treatment-Emergent Hypertension in de Novo Metastatic Hormone-Sensitive Prostate Cancer
Jean Philippe Theurillat – The Prostate Cancer Atlas: A Next Generation Tool to Investigate Cancer Progression for Biomarker and Drug Target Discovery and Validation
11h00
PARALLEL SESSION: CARDIOLOGY

Chairs: Lucio Barile and Giulio Conte
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Claudia Altomare – Senescence-induced electrical instability: from single cell to monolayer tissue functional properties
Luigi Biasco – Derivation and validation of an AI based score to predict mortality at 12, 24, 36 and 48 months in patients with primary and secondary mitral regurgitation treated by transcatheter edge-to-edge repair.
Marialuce Caputo – Release velocity ImprovemenT with a new Metronome-guIded chest COmpression protocol: results of the multicenter RITMICO study
David Constantin Filip – Prognostic impact of right ventricle-pulmonary artery coupling improvement after mitral valve transcatheter edge-to-edge repair
Sven Lifka – Prognostic significance of left atrial function in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.
Giuliana Monachino – Life-Threatening Arrhythmias detection: learning from a massive dataset
Alessia D’Alto (Tardu Özkartal) – Impact of comorbidity on complication rates and life expectancy in patients with a leadless pacemaker
Anna Giulia Pavon – Cardio-Hepatic Axis in STEMI: evaluating Hepatic T1 mapping as a novel biomarker for early detection and prognostication of Heart Failure.
11h00
PARALLEL SESSION: NEUROLOGICAL SCIENCES 1

Chairs: Silvia Miano and Chiara Zecca
7 Oral presentations (Presentation 6 min + Discussion 2 min)

Marco Barbero (Daniele Lonati) – Validation of a digital dynamometer for assessing the cranio-cervical flexion test in volunteers with and without neck pain
Rudolf Kälin – The prognostic value of plasma-derived extracellular vesicle surface antigens in Parkinson’s disease patients
Alessandro Puiatti – Assistive Device for Autonomous Navigation for blind and visually impaired peopleRosaria Sacco – Memory B cell–guided extended interval dosing of ocrelizumab in multiple sclerosis
Radoslava Švihrová – Wearables and sleep: effect of circadian rhythm disruption on sleep quality, recovery and well-being
Giorgia Melli (Ankush Yadav) – Plasma-derived extracellular vesicles of patients with Parkinson’s disease cause neurodegeneration through microglia activation
11h00
PARALLEL SESSION: NURSING 1

Chairs: Loris Bonetti and Sarah Liptrott
6 Oral presentations (Presentation 6 min + Discussion 3 min)

Marta Aramini – Development of the Advanced Practice Nurse (APN) role for peritoneal dialysis patients: a qualitative research study
Loris Bonetti (Isabelle Ballabio Messina) – Alimentazione degli infermieri turnisti in Ticino e fattori influenzanti le scelte alimentari: studio osservazionale trasversale
Celine Beffa – Experiences of non-specialized emergency nurses awaiting specialization in a pre-training path: a qualitative descriptive study
Corina Elena Luca – Development of a complex intervention to promote civil workplaces among hospital nursing teams: a multistage sequential explanatory mixed-method framework study
Rachele Baudino (Claudio Speroni) – Implementation of a flexible nurse staffing “Team Fix” model at the Regional Hospital of Lugano
Vania Pedroia – Improving care of dysphagic patient in the Department of Internal Medicine 2 (EOC-OSG)
12h10
LUNCH BREAK
12h10
POSTER SESSION

(VOTING SESSION BY THE JURY)
13h10
KEYNOTE LECTURE

Discussant: Emiliano Albanese
Title: Transparent reporting of health research: challenges and solutions
Erik von Elm, MD MSc FMH, Director Cochrane Switzerland, Lausanne
Centre universitaire de médecine générale et santé publique (Unisanté)
13h30
TOP RATED ORAL PRESENTATIONS: SESSION 2

(VOTING SESSION BY PARTICIPANTS IN PRESENCE AND ONLINE)

Chairs:Greta Guarda and Anastasios Stathis

7 Oral presentations (Presentation 7 min + Discussion 3 min)

Domenico Albino – Proteomic analysis of extracellular vesicles reveals novel markers of prostate cancer progression
Maria Teresa Balia – Exploring the immunomodulatory functions of PARP Inhibitors in ER-Positive Breast Cancer
Letizia Boffa – Exploring the contribution of the immune compartment in BRCA-dependent cancer onset
Marco Bongiovanni – The CArbapenem-Sparing-Antimicrobial-Stewardship (CASAS) Project: an innovative approach to reduce carbapenem consumption in low-users hospital settings
Manuel Colucci – Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
Daniela Impellizzieri – Antibody-based therapeutics for metastatic hormone-refractory prostate cancer
Ji Zhang – An Integrated Proteomic Portrait of Prostate Cancer Progression Reveals New Therapeutic Opportunities
14h40
COFFEE BREAK
15h00
PARALLEL SESSION: ONCOLOGY 2 AND MISCELLANEOUS

Chairs: Arianna Baggiolini and Mattia Rizzi
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Alberto Arribas – CRISPR/Cas9 screening identifies genes affecting the sensitivity to the copanlisib/venetoclax combination in lymphoma
Camilla Sculco (Beatrice Bano) – (Fear of) SARS-CoV-2 infection and psychological distress: prospective seroprevalence study in southern Switzerland
Martina Bellafante – Defining the epigenetic landscape regulating a progenitor signature in development and melanoma initiation and progression
Lorenzo Cavallini – Design and Feasibility Study of an Aortic Turbine for Self-Powered Implantable Medical Devices
Elisa Federici – Novel treatment strategies for hepatocellular carcinoma: rewiring the cancer cell transcriptome by CDK9 inhibition
Fabio Bergamini (Bernhard Gerber) – 3 years follow-up of Venetoclax in Relapsed or Refractory AL Amyloidosis with t(11;14) and BCL2 expression
Lorenzo Ruinelli – Electronic Health Records to recognize and predict Acute Kidney Injury and Disease
Antonietta Verrillo – The role of neuronal-cancer crosstalk in human melanoma brain metastases
15h00
PARALLEL SESSION: IMMUNOLOGY AND BEYOND

Chairs: Giandomenica Iezzi
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Vanessa Biemmi – Syndecan-Syntenin-Alix complex mediates SRC function in macrophages’ small-EV release
Carolin Hoefner – Investigating Lysosomal Clearance of Endoplasmic Reticulum Domains as Induced by accumulation of Membrane-Bound Misfolded Proteins
Veronica Martini – A CD8 T-cell subset with osteogenic and cytotoxic properties: a potential therapeutic target in ankylosing spondylitis
Diego Morone – Role of autophagy in T cell homeostasis
Francesca Righetti – Dissect the role of intracellular bacteria in cancer neutrophil evolution
Anna Rinaldi – Identification of a novel senolytic compound to prevent chronic kidney injury and fibrosis
Francesca Silini – Understanding the connections between cellular metabolism, MHCI regulation, and the immune response
Virginia Sitta – The Impact of Gut Microbiota on Anastomotic Leakage After Colorectal Surgery (MicrobAL)
15h00
PARALLEL SESSION: NEUROLOGICAL SCIENCES 2

Chairs: Marco Barbero and Matteo Moretti
6 Oral presentations (Presentation 6 min + Discussion 2 min)

Marco Barbero – Concurrent validity and reliability of a novel algometer for measuring pressure pain thresholds in healthy volunteers
Stefano Vercelli (Matteo Beretta-Piccoli) – Cross-cultural translation, validation, reliability, and minimal clinical important difference of the Italian Pittsburgh Fatigability Scale
Laura Guerricchio – Extracellular Vesicles from II Trimester Amniotic Fluid: Novel Therapeutic for Skeletal and Cardiac Muscle Injury
Megi Ishmaku – Biofabrication of a 3D model of human skeletal muscle for the study of fibrosis
Eva Koetsier – Lumbar Facet Joint Radiofrequency Ablation with a 3-Tined Cannula, a Technical Report and Observational Study
Ismaiel Zaed – Long-Term Follow-Up of Custom-Made Porous Hydroxyapatite Cranioplasties: Analysis of Infections in Adult and Pediatric Patients
15h00
PARALLEL SESSION: NURSING 2

Chairs: Loris Bonetti
5 Oral presentations (Presentation 6 min + Discussion 3 min)

Tatiana Bolgeo – Anorectal Malformation and Hirschsprung’s Disease: assessing the effectiveness of faecal incontinence rehabilitation in paediatric patients.
Anna Bottani – A qualitative study of obstetric violence in Western Switzerland. Midwifery students report their representations and needs regarding “obstetric violence”
Susanna Calcaterra – “Imparare facendo”: acquisire competenze nell’ambulatorio di emodialisi dell’Ospedale Regionale di Lugano attraverso le simulazioni
Simone Nasi – Migliorare nella presa a carico di pazienti con ferite/lesioni presso la sede di Acquarossa
Antonio Palermo – Components of a complex intervention to develop clinical leadership of the specialist Nurse: qualitative study
16h20
Awards Ceremony

Chairs: Greta Guarda e Giorgio Treglia with

Farma Industria Ticino, Piero Poli (Rivopharm SA), Chair
Swiss Medtech, Giuseppe Perale, Executive VP & Founder I.B.I. SA, Regenera SA, Chair Swiss Medtech Ticino

– Best poster clinical and epidemiological research*
– Best poster basic, translational and computational research*
– Best poster nursing research*

*These awards are assigned during the event by the Jury (Guarda / Treglia / Bonetti / Di Tanna)

– Best oral presentation clinical and epidemiological research**
– Best oral presentatio basic, translational and computational research**
– Best oral presentation nursing research**

**These awards are assigned during the TOP RATED SESSION 1 AND 2 by vote of participants in presence and online
16h40
Closing
17h00
Aperitif

PARALLEL SESSION:
ONCOLOGY 1

11h00
PARALLEL SESSION: Oncology

Chairs: Arianna Calcinotto and Alessandra Franzetti-Pellanda
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Clemence Aellen – Efficacy of intraoperative widening of surgical resection margins of non-palpable breast cancer
Gaston Fabian Dellaferrera – Recurrence after resection for non-small cell lung cancer: risk factors by stage molecular profile
Chiara Fasana – The immune landscape of epithelial ovarian cancer
Maria Luisa Gasparri – Radar localization for targeted axillary dissection in breast cancer patients undergoing primary systemic
treatment
Cindy Garda – Myeloid cells impact HER2 expression in breast cancer, affecting response to HER2-targeted therapy
Concetta Guerra – An antibody-based strategy targeting oncogenic mERG in prostate cancer
Giuseppe Salfi – Prognostic Implications of Early Treatment-Emergent Hypertension in de Novo Metastatic Hormone-Sensitive
Prostate Cancer
Jean Philippe Theurillat – The Prostate Cancer Atlas: A Next Generation Tool to Investigate Cancer Progression for Biomarker and
Drug Target Discovery and Validation
12h00
END OF PARALLEL SESSION ONCOLOGY

PARALLEL SESSION:
CARDIOLOGY

11h00
PARALLEL SESSION: Cardiology

Chairs: Lucio Barile and Giulio Conte
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Azucena Rendon-Angel (Claudia Altomare) – Senescence-induced electrical instability: from single cell to monolayer tissue functional
properties
Luigi Biasco – Derivation and validation of an AI based score to predict mortality at 12, 24, 36 and 48 months in patients with
primary and secondary mitral regurgitation treated by transcatheter edge-to-edge repair.
Marialuce Caputo – Release velocity ImprovemenT with a new Metronome-guIded chest COmpression protocol: results of the
multicenter RITMICO study
David Constantin Filip – Prognostic impact of right ventricle-pulmonary artery coupling improvement after mitral valve transcatheter
edge-to-edge repair
Sven Lifka – Prognostic significance of left atrial function in patients with severe aortic stenosis undergoing transcatheter aortic
valve replacement.
Giuliana Monachino – Life-Threatening Arrhythmias detection: learning from a massive dataset
Alessia D’Alto (Tardu Özkartal) – Impact of comorbidity on complication rates and life expectancy in patients with a leadless
pacemaker
Anna Giulia Pavon – Cardio-Hepatic Axis in STEMI: evaluating Hepatic T1 mapping as a novel biomarker for early detection and
prognostication of Heart Failure.
12h00
END OF PARALLEL SESSION CARDIOLOGY

PARALLEL SESSION:
NEUROLOGICAL SCIENCES 1

11h00
PARALLEL SESSION: Neurological Sciences 1

Chairs: Silvia Miano and Chiara Zecca
6 Oral presentations (Presentation 6 min + Discussion 2 min)

Marco Barbero (Daniele Lonati) – Validation of a digital dynamometer for assessing the cranio-cervical flexion test in volunteers
with and without neck pain
Rudolf Kälin – The prognostic value of plasma-derived extracellular vesicle surface antigens in Parkinson’s disease patients
Alessandro Puiatti – Assistive Device for Autonomous Navigation for blind and visually impaired peopleRosaria Sacco – Memory B
cell–guided extended interval dosing of ocrelizumab in multiple sclerosis
Radoslava Švihrová – Wearables and sleep: effect of circadian rhythm disruption on sleep quality, recovery and well-being
Giorgia Melli (Ankush Yadav) – Plasma-derived extracellular vesicles of patients with Parkinson’s disease cause neurodegeneration
through microglia activation
Michele Pio Fabrizio – Growth and rupture of an intracranial aneurysm: the role of wall aneurysmal enhancement and CD68
12h00
END OF PARALLEL SESSION NEUROLOGICAL SCIENCES 1

PARALLEL SESSION:
NURSING 1

11h00
PARALLEL SESSION: NURSING 1

Chairs: Loris Bonetti and Sarah Liptrott
6 Oral presentations (Presentation 6 min + Discussion 3 min)

Marta Aramini – Development of the Advanced Practice Nurse (APN) role for peritoneal dialysis patients: a qualitative research
study
Loris Bonetti (Isabelle Ballabio Messina) – Alimentazione degli infermieri turnisti in Ticino e fattori influenzanti le scelte alimentari:
studio osservazionale trasversale
Celine Beffa – Experiences of non-specialized emergency nurses awaiting specialization in a pre-training path: a qualitative
descriptive study
Corina Elena Luca – Development of a complex intervention to promote civil workplaces among hospital nursing teams: a multistage
sequential explanatory mixed-method framework study
Rachele Baudino (Claudio Speroni) – Implementation of a flexible nurse staffing “Team Fix” model at the Regional Hospital of
Lugano
Vania Pedroia – Improving care of dysphagic patient in the Department of Internal Medicine 2 (EOC-OSG)
12h00
END OF PARALLEL SESSION NURSING 1

PARALLEL SESSION:
ONCOLOGY 2 ANDMISCELLANEOUS

15h00
PARALLEL SESSION: Oncology 2 and Miscellaneous

Chairs: Arianna Baggiolini and Mattia Rizzi
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Alberto Arribas – CRISPR/Cas9 screening identifies genes affecting the sensitivity to the copanlisib/venetoclax combination in
lymphoma
Camilla Sculco (Beatrice Bano) – (Fear of) SARS-CoV-2 infection and psychological distress: prospective seroprevalence study in
southern Switzerland
Martina Bellafante – Defining the epigenetic landscape regulating a progenitor signature in development and melanoma initiation
and progression
Lorenzo Cavallini – Design and Feasibility Study of an Aortic Turbine for Self-Powered Implantable Medical Devices
Elisa Federici – Novel treatment strategies for hepatocellular carcinoma: rewiring the cancer cell transcriptome by CDK9 inhibition
Fabio Bergamini (Bernhard Gerber) – 3 years follow-up of Venetoclax in Relapsed or Refractory AL Amyloidosis with t(11;14) and
BCL2 expression
Lorenzo Ruinelli – Electronic Health Records to recognize and predict Acute Kidney Injury and Disease
Antonietta Verrillo – The role of neuronal-cancer crosstalk in human melanoma brain metastases
16h00
END OF PARALLEL SESSION ONCOLOGY 2 AND MISCELLANEOUS

PARALLEL SESSION:
IMMUNOLOGY AND BEYOND

15h00
PARALLEL SESSION: IMMUNOLOGY AND BEYOND

Chairs: Giandomenica Iezzi and Luca Varani
8 Oral presentations (Presentation 6 min + Discussion 2 min)

Vanessa Biemmi – Syndecan-Syntenin-Alix complex mediates SRC function in macrophages’ small-EV release
Carolin Hoefner – Investigating Lysosomal Clearance of Endoplasmic Reticulum Domains as Induced by accumulation of Membrane-
Bound Misfolded Proteins
Veronica Martini – A CD8 T-cell subset with osteogenic and cytotoxic properties: a potential therapeutic target in ankylosing
spondylitis
Diego Morone – Role of autophagy in T cell homeostasis
Francesca Righetti – Dissect the role of intracellular bacteria in cancer neutrophil evolution
Anna Rinaldi – Identification of a novel senolytic compound to prevent chronic kidney injury and fibrosis
Francesca Silini – Understanding the connections between cellular metabolism, MHCI regulation, and the immune response
Virginia Sitta – The Impact of Gut Microbiota on Anastomotic Leakage After Colorectal Surgery (MicrobAL)
16h00
END OF PARALLEL SESSION IMMUNOLOGY AND BEYOND

PARALLEL SESSION:
NEUROLOGICAL SCIENCES 2

15h00
PARALLEL SESSION: NEUROLOGICAL SCIENCES 2

Chairs: Marco Barbero and Matteo Moretti
6 Oral presentations (Presentation 6 min + Discussion 2 min)

Marco Barbero – Concurrent validity and reliability of a novel algometer for measuring pressure pain thresholds in healthy
volunteers
Stefano Vercelli (Matteo Beretta-Piccoli) – Cross-cultural translation, validation, reliability, and minimal clinical important difference
of the Italian Pittsburgh Fatigability Scale
Laura Guerricchio – Extracellular Vesicles from II Trimester Amniotic Fluid: Novel Therapeutic for Skeletal and Cardiac Muscle
Injury
Megi Ishmaku – Biofabrication of a 3D model of human skeletal muscle for the study of fibrosis
Eva Koetsier – Lumbar Facet Joint Radiofrequency Ablation with a 3-Tined Cannula, a Technical Report and Observational Study
Michele Pio Fabrizio (Ismaiel Zaed) – Long-Term Follow-Up of Custom-Made Porous Hydroxyapatite Cranioplasties: Analysis of
Infections in Adult and Pediatric Patients
16h00
END OF PARALLEL SESSION NEUROLOGICAL SCIENCES 2

PARALLEL SESSION:
NURSING 2

15h00
PARALLEL SESSION: NURSING 2

Chairs: Loris Bonetti and Michele Villa
5 Oral presentations (Presentation 6 min + Discussion 3 min)

Menada Gardalini (Tatiana Bolgeo) – Anorectal Malformation and Hirschsprung’s Disease: assessing the effectiveness of faecal
incontinence rehabilitation in paediatric patients.
Anna Bottani – A qualitative study of obstetric violence in Western Switzerland. Midwifery students report their representations
and needs regarding “obstetric violence”
Susanna Calcaterra – “Imparare facendo”: acquisire competenze nell’ambulatorio di emodialisi dell’Ospedale Regionale di Lugano
attraverso le simulazioni
Simone Nasi – Migliorare nella presa a carico di pazienti con ferite/lesioni presso la sede di Acquarossa
Antonio Palermo – Components of a complex intervention to develop clinical leadership of the specialist Nurse: qualitative study
16h00
END OF PARALLEL SESSION NURSING 2

POSTER SESSION

12h15

SURGERY AND CRITICAL CARE

ONCOLOGY

NURSING

CARDIOLOGY

NEUROSCIENCES

COMPUTATIONAL MEDICINE

INFORMATICS

PEDIATRICS

PHARMACOLOGY

REHABILITATION

INFECTIOUS DISEASES

ENDOCRINOLOGY

IMAGING

EPIDEMIOLOGY

NUTRITION

REGENERATIVE MEDICINE
13h15
END OF POSTER SESSION

SUPPORT AND COLLABORATION

With the support and collaboration of:

HOW TO REACH THE EVENT

Event location: USI Campus Est, Settore A, Via la Santa 1, Lugano-Viganello

BY TRAIN Recommended!

Reach the Lugano train station. From the station, the campus can be reached by bus or by foot.

BY BUS Recommended!

Take the bus 6 (towards “Cornaredo”), which departs from the forecourt in front of the station; get off at the ‘Campus Universitario’ stop (approx. 8-10 minutes’ journey under normal traffic conditions).

See directions on the map.

BY FOOT Recommended!

From the station square go down Via Zurigo until you reach Corso Elvezia on the left and continue along Via Madonnetta until you reach the bridge, cross it and the EST campus is on your left after crossing the bridge.

See directions on the map.

BY CAR STRONGLY DISCOURAGED!

A2 Highway: take the Lugano Nord exit, Autostrada Lugano Nord. Proceed in south direction on Lugano Nord Highway
44 s (800 m), Take Via Besso towards Via S. Gottardo 5 min (1,5 km). Continue on Via S. Gottardo 57 s (450 m). Continue on Via Zurigo. Drive towards Via la Santa 5 min (1,8 km). Arrival at Campus EST USI Via la Santa 1, 6962 Lugano

Shortly after the traffic lights, the entrance to the campus underground car park is visible on the left. See route on the map

IMPORTANT IF YOU CANNOT REACH THE EVENT WITHOUT A CAR

A parking alternative in the immediate vicinity of the campus is the Autosilo dell’Ospedale Italiano di Lugano (accessible from Via agli Orti): See route on the map
You can find other car parks in the area at the following link: https://www.lugano.ch/mobilita-sicurezza/parcheggi-e-autosili.html